Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT01417663

Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function

Combining Exercise Training With a Drug to Break AGE-crosslinks; Effects on Cardiovascular Structure and Function and Related Mechanisms

Sponsor: Dutch Heart Foundation

Conditions Aging Cardiovascular Disease Endothelial Dysfunction Physical Activity

Interventions Alt-711 Physical exercise training

Updated 7 times since 2017 Last updated: Sep 6, 2013 Started: Nov 30, 2008 Primary completion: Jun 30, 2011 Completion: Jun 30, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2/PHASE3 clinical study on Aging and Cardiovascular Disease, this trial is completed. The trial is conducted by Dutch Heart Foundation and has accumulated 7 data snapshots since 2008. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE2/PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2/PHASE3

Phase: PHASE2_PHASE3 → PHASE2/PHASE3
Mar 2022 — Jul 2024 [monthly]

Completed PHASE2_PHASE3
Jan 2021 — Mar 2022 [monthly]

Completed PHASE2_PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2_PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE2_PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2_PHASE3

First recorded

Nov 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Dutch Heart Foundation
Radboud University Medical Center
Synvista Therapeutics, Inc

Data source: Radboud University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Nijmegen, Netherlands