deltatrials
Completed NA INTERVENTIONAL 3-arm NCT01441856

The ORANGE II PLUS - Trial: Open Versus Laparoscopic Hemihepatectomy

The ORANGE II PLUS - Trial: an International Multicenter Randomized Controlled Trial of Open Versus Laparoscopic Hemihepatectomies.

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Updated 15 times since 2017 Last updated: May 16, 2025 Started: Oct 1, 2013 Primary completion: Dec 4, 2019 Completion: Dec 4, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01441856, this NA trial focuses on Liver Lesions Requiring Hemihepatectomy and remains completed. Sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), it has been updated 15 times since 2013, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Apr 2017 · 3 months · monthly snapshot~Apr 2017 – ~Jun 2018 · 14 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Jan 2019 · 6 months · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~Feb 2020 · 11 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Dec 2020 · 9 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jan 2024 · 33 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – present · 15 months · monthly snapshot

Change History

15 versions recorded
  1. Jun 2025 — Present [monthly]

    Completed NA

    Status: UnknownCompleted

  2. Sep 2024 — Jun 2025 [monthly]

    Unknown NA

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown NA

    Status: Unknown StatusUnknown

  4. Jan 2024 — Jul 2024 [monthly]

    Unknown Status NA

    Status: Active Not RecruitingUnknown Status

  5. Apr 2021 — Jan 2024 [monthly]

    Active Not Recruiting NA

Show 10 earlier versions
  1. Jan 2021 — Apr 2021 [monthly]

    Active Not Recruiting NA

  2. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

  3. Mar 2020 — Dec 2020 [monthly]

    Active Not Recruiting NA

  4. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting NA

  5. Mar 2019 — Feb 2020 [monthly]

    Active Not Recruiting NA

  6. Jan 2019 — Mar 2019 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

  7. Jul 2018 — Jan 2019 [monthly]

    Recruiting NA

  8. Jun 2018 — Jul 2018 [monthly]

    Recruiting NA

  9. Apr 2017 — Jun 2018 [monthly]

    Recruiting NA

  10. Jan 2017 — Apr 2017 [monthly]

    Recruiting NA

    First recorded

Oct 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
  • Derriford Hospital
  • General Hospital Groeninge
  • Jessa Hospital
  • King's College London
  • Liverpool University Hospitals NHS Foundation Trust
  • Maastricht University Medical Center
  • Newcastle-upon-Tyne Hospitals NHS Trust
  • Oslo University Hospital
  • Oxford University Hospitals NHS Trust
  • Queen Elizabeth Hospital NHS Foundation Trust
  • San Raffaele University Hospital, Italy
  • Universitair Ziekenhuis Brussel
  • University Hospital Southampton NHS Foundation Trust
  • University Hospital, Aachen
  • University Hospital, Ghent
Data source: Maastricht University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .