deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT01464164

Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia (ACE-011-DBA)

Phase I/II, Open-Label Study to Determine Safety and Efficacy of Sotatercept (ACE-011) in Adults With Red Blood Cell Transfusion- Dependent Diamond Blackfan Anemia

Sponsor: Northwell Health

Conditions Diamond Blackfan Anemia
Interventions Sotatercept Sotatercept with prednisone boost
Updated 13 times since 2017 Last updated: Feb 27, 2023 Started: Jan 31, 2012 Primary completion: Apr 13, 2021 Completion: Apr 13, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Supporter terminated the study due to no active patients (secondary to travel restrictions due to COVID).

Other terminated trials from Northwell Health

See all terminations from Northwell Health

Other Diamond Blackfan Anemia trials with similar outcome

Browse all Diamond Blackfan Anemia trials

Listed as NCT01464164, this PHASE1/PHASE2 trial focuses on Diamond Blackfan Anemia and remains terminated or withdrawn. Sponsored by Northwell Health, it has been updated 13 times since 2012, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Feb 2018 · 12 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Mar 2020 · 9 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jan 2022 · 9 months · monthly snapshot~Jan 2022 – ~Apr 2023 · 15 months · monthly snapshot~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 24 months · monthly snapshot

Change History

13 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  3. Apr 2023 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

  4. Jan 2022 — Apr 2023 [monthly]

    Terminated PHASE1_PHASE2

    Status: Recruiting → Terminated

  5. Apr 2021 — Jan 2022 [monthly]

    Recruiting PHASE1_PHASE2

▶ Show 8 earlier versions

  1. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE1_PHASE2

  2. Mar 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jun 2019 — Mar 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Active Not Recruiting → Recruiting

  4. Apr 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  5. Jun 2018 — Apr 2019 [monthly]

    Recruiting PHASE1_PHASE2

  6. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

  7. Feb 2017 — Feb 2018 [monthly]

    Recruiting PHASE1_PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Jan 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Northwell Health
Data source: Northwell Health

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations