deltatrials
Unknown PHASE2 INTERVENTIONAL 2-arm NCT01466114

Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

A Double-Blind, Placebo Controlled Trial of Estriol Treatment in Women With Multiple Sclerosis: Effect on Cognition.

Sponsor: University of California, Los Angeles

Conditions Primary-progressive Multiple Sclerosis Relapsing-remitting Multiple Sclerosis Secondary-progressive Multiple Sclerosis
Interventions Norethindrone Placebo Progestin Placebo estriol
Updated 10 times since 2017 Last updated: Nov 4, 2019 Started: Oct 31, 2011 Primary completion: Dec 31, 2021 Completion: Apr 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01466114, this PHASE2 trial focuses on Primary-progressive Multiple Sclerosis and Relapsing-remitting Multiple Sclerosis and remains ongoing. Sponsored by University of California, Los Angeles, it has been updated 10 times since 2011, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~May 2017 · 3 months · monthly snapshotRecruiting~May 2017 – ~Jun 2018 · 13 months · monthly snapshotRecruiting~Jun 2018 – ~May 2019 · 11 months · monthly snapshotRecruiting~May 2019 – ~Dec 2019 · 7 months · monthly snapshotUnknown Status~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshotRecruiting~Jan 2021 – ~May 2022 · 16 months · monthly snapshotRecruiting~May 2022 – ~Jul 2024 · 26 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – present · 22 months · monthly snapshotUnknown

Change History

10 versions recorded

  1. Sep 2024 — Present [monthly]

    Unknown PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown Status → Unknown

  3. May 2022 — Jul 2024 [monthly]

    Unknown Status PHASE2

    Status: Recruiting → Unknown Status

  4. Jan 2021 — May 2022 [monthly]

    Recruiting PHASE2

  5. Dec 2019 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Unknown Status → Recruiting

▶ Show 5 earlier versions

  1. May 2019 — Dec 2019 [monthly]

    Unknown Status PHASE2

    Status: Recruiting → Unknown Status

  2. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE2

  3. May 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  4. Feb 2017 — May 2017 [monthly]

    Recruiting PHASE2

  5. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Oct 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of California, Los Angeles
Data source: University of California, Los Angeles

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations