deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 6-arm NCT01485861

Study of Ipatasertib or Apitolisib With Abiraterone Acetate Versus Abiraterone Acetate in Participants With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel Chemotherapy

A Phase Ib/II Study of Ipatasertib (GDC-0068) or Apitolisib (GDC-0980) With Abiraterone Acetate Versus Abiraterone Acetate in Patients With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy

Sponsor: Genentech, Inc.

Updated 35 times since 2017 Last updated: Aug 17, 2023 Started: Jan 11, 2012 Primary completion: Sep 1, 2015 Completion: Aug 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Prostate Cancer and is currently completed. Genentech, Inc. leads this study, which shows 35 recorded versions since 2012 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Jul 2017 · 3 months · monthly snapshot~Jul 2017 – ~Jan 2018 · 6 months · monthly snapshot~Jan 2018 – ~Apr 2018 · 3 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Nov 2018 · 4 months · monthly snapshot~Nov 2018 – ~Mar 2019 · 4 months · monthly snapshot~Mar 2019 – ~May 2019 · 2 months · monthly snapshot~May 2019 – ~Sep 2019 · 4 months · monthly snapshot~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Oct 2023 · 13 months · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

35 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Oct 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  5. Sep 2022 — Oct 2023 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

Show 30 earlier versions
  1. May 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Feb 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Nov 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  4. Sep 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  5. Apr 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  6. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE1_PHASE2

  7. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE1_PHASE2

  9. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  10. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1_PHASE2

  11. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1_PHASE2

  12. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE1_PHASE2

  13. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE1_PHASE2

  14. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE1_PHASE2

  15. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1_PHASE2

  16. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE1_PHASE2

  17. Jan 2020 — Mar 2020 [monthly]

    Recruiting PHASE1_PHASE2

  18. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Active Not RecruitingRecruiting

  19. Sep 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  20. May 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  21. Mar 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  22. Nov 2018 — Mar 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  23. Jul 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  24. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  25. Apr 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  26. Jan 2018 — Apr 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  27. Jul 2017 — Jan 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  28. Apr 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  29. Feb 2017 — Apr 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  30. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    First recorded

Jan 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Genentech, Inc.
Data source: Genentech, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .