Completed PHASE3 INTERVENTIONAL 2-arm NCT01508702

Lesinurad Monotherapy in Gout Subjects Intolerant to Xanthine Oxidase Inhibitors (LIGHT)

A Phase 3 Randomized, Double-Blind, Multicenter, Placebo- Controlled Study to Assess the Efficacy and Safety of Lesinurad Monotherapy Compared to Placebo in Subjects With Gout and an Intolerance or Contraindication to a Xanthine Oxidase Inhibitor

Sponsor: Ardea Biosciences, Inc.

Conditions Gout

Interventions Placebo lesinurad

Updated 7 times since 2017 Last updated: Jan 14, 2016 Started: Jan 31, 2012 Primary completion: Oct 31, 2013 Completion: Nov 30, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01508702, this PHASE3 trial focuses on Gout and remains completed. Sponsored by Ardea Biosciences, Inc., it has been updated 7 times since 2012, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Jan 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Ardea Biosciences, Inc.

Data source: Ardea Biosciences, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Anaheim, United States , Anderlecht, Belgium , Auckland, New Zealand , Birmingham, United States , Boynton Beach, United States , Brentwood, United States , Brooklyn, United States , Butterfield, Australia , Carmichael, United States and 89 more locations