deltatrials
Completed NA INTERVENTIONAL 5-arm NCT01511614

Nicotine Withdrawal Symptoms and Smoking Relapse

Identifying Neurobiological Mechanisms That Underlie Acute Nicotine Withdrawal and Drive Early Relapse in Smokers

Sponsor: National Institute on Drug Abuse (NIDA)

Conditions Nicotine Dependence
Interventions Motivational Interviewing Nicotine patch Placebo patch Placebo pill Transcranial Direct Current Stimulation Varenicline Pill sham
Updated 52 times since 2017 Last updated: May 30, 2024 Started: May 20, 2013 Primary completion: Mar 30, 2020 Completion: Mar 30, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Nicotine Dependence, this trial is completed. The trial is conducted by National Institute on Drug Abuse (NIDA) and has accumulated 52 data snapshots since 2013. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Nov 2017 · 9 months · monthly snapshot~Nov 2017 – ~Apr 2018 · 5 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jun 2021 · 4 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Jan 2023 · 2 months · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Jun 2024 · 10 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 23 months · monthly snapshot

Change History

52 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed NA

  2. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  3. Jun 2024 — Jul 2024 [monthly]

    Completed NA

  4. Aug 2023 — Jun 2024 [monthly]

    Completed NA

    Status: Suspended → Completed

  5. Jul 2023 — Aug 2023 [monthly]

    Suspended NA

▶ Show 47 earlier versions

  1. Jun 2023 — Jul 2023 [monthly]

    Suspended NA

  2. May 2023 — Jun 2023 [monthly]

    Suspended NA

  3. Apr 2023 — May 2023 [monthly]

    Suspended NA

  4. Feb 2023 — Apr 2023 [monthly]

    Suspended NA

  5. Jan 2023 — Feb 2023 [monthly]

    Suspended NA

  6. Nov 2022 — Jan 2023 [monthly]

    Suspended NA

  7. Sep 2022 — Nov 2022 [monthly]

    Suspended NA

    Status: Recruiting → Suspended

  8. Jul 2022 — Sep 2022 [monthly]

    Recruiting NA

  9. Jun 2022 — Jul 2022 [monthly]

    Recruiting NA

  10. May 2022 — Jun 2022 [monthly]

    Recruiting NA

  11. Apr 2022 — May 2022 [monthly]

    Recruiting NA

  12. Jan 2022 — Apr 2022 [monthly]

    Recruiting NA

  13. Dec 2021 — Jan 2022 [monthly]

    Recruiting NA

  14. Oct 2021 — Dec 2021 [monthly]

    Recruiting NA

  15. Sep 2021 — Oct 2021 [monthly]

    Recruiting NA

  16. Jun 2021 — Sep 2021 [monthly]

    Recruiting NA

  17. Feb 2021 — Jun 2021 [monthly]

    Recruiting NA

  18. Jan 2021 — Feb 2021 [monthly]

    Recruiting NA

  19. Dec 2020 — Jan 2021 [monthly]

    Recruiting NA

  20. Nov 2020 — Dec 2020 [monthly]

    Recruiting NA

  21. Oct 2020 — Nov 2020 [monthly]

    Recruiting NA

  22. Sep 2020 — Oct 2020 [monthly]

    Recruiting NA

  23. Jul 2020 — Sep 2020 [monthly]

    Recruiting NA

  24. Apr 2020 — Jul 2020 [monthly]

    Recruiting NA

    Phase: None → NA

  25. Jan 2020 — Apr 2020 [monthly]

    Recruiting

  26. Dec 2019 — Jan 2020 [monthly]

    Recruiting

  27. Nov 2019 — Dec 2019 [monthly]

    Recruiting

  28. Oct 2019 — Nov 2019 [monthly]

    Recruiting

  29. Sep 2019 — Oct 2019 [monthly]

    Recruiting

  30. Aug 2019 — Sep 2019 [monthly]

    Recruiting

  31. Jul 2019 — Aug 2019 [monthly]

    Recruiting

  32. Jun 2019 — Jul 2019 [monthly]

    Recruiting

  33. May 2019 — Jun 2019 [monthly]

    Recruiting

  34. Apr 2019 — May 2019 [monthly]

    Recruiting

  35. Mar 2019 — Apr 2019 [monthly]

    Recruiting

  36. Feb 2019 — Mar 2019 [monthly]

    Recruiting

  37. Jan 2019 — Feb 2019 [monthly]

    Recruiting

  38. Nov 2018 — Jan 2019 [monthly]

    Recruiting

  39. Oct 2018 — Nov 2018 [monthly]

    Recruiting

  40. Sep 2018 — Oct 2018 [monthly]

    Recruiting

  41. Aug 2018 — Sep 2018 [monthly]

    Recruiting

  42. Jul 2018 — Aug 2018 [monthly]

    Recruiting

  43. Jun 2018 — Jul 2018 [monthly]

    Recruiting

  44. Apr 2018 — Jun 2018 [monthly]

    Recruiting

    Phase: NA → None

  45. Nov 2017 — Apr 2018 [monthly]

    Recruiting NA

  46. Feb 2017 — Nov 2017 [monthly]

    Recruiting NA

  47. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

May 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute on Drug Abuse (NIDA)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations