deltatrials
Completed NA INTERVENTIONAL 3-arm NCT01531374

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Medtronic CoreValve® Continued Access Study

Sponsor: Medtronic Cardiovascular

Conditions Severe Aortic Stenosis
Interventions Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)
Updated 25 times since 2017 Last updated: Oct 21, 2022 Started: Feb 21, 2012 Primary completion: Nov 30, 2015 Completion: Nov 18, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Severe Aortic Stenosis and is currently completed. Medtronic Cardiovascular leads this study, which shows 25 recorded versions since 2012 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~May 2018 · 9 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Apr 2019 · 5 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Dec 2019 · 6 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~May 2020 · 4 months · monthly snapshot~May 2020 – ~Sep 2020 · 4 months · monthly snapshot~Sep 2020 – ~Dec 2020 · 3 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Dec 2021 · 6 months · monthly snapshot~Dec 2021 – ~May 2022 · 5 months · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Nov 2022 · 4 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

25 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed NA

  2. Sep 2024 — Sep 2025 [monthly]

    Completed NA

  3. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  4. Jan 2023 — Jul 2024 [monthly]

    Completed NA

  5. Dec 2022 — Jan 2023 [monthly]

    Completed NA

▶ Show 20 earlier versions

  1. Nov 2022 — Dec 2022 [monthly]

    Completed NA

  2. Jul 2022 — Nov 2022 [monthly]

    Completed NA

  3. May 2022 — Jul 2022 [monthly]

    Completed NA

  4. Dec 2021 — May 2022 [monthly]

    Completed NA

  5. Jun 2021 — Dec 2021 [monthly]

    Completed NA

  6. Jan 2021 — Jun 2021 [monthly]

    Completed NA

  7. Dec 2020 — Jan 2021 [monthly]

    Completed NA

    Status: Active Not Recruiting → Completed

  8. Sep 2020 — Dec 2020 [monthly]

    Active Not Recruiting NA

  9. May 2020 — Sep 2020 [monthly]

    Active Not Recruiting NA

  10. Jan 2020 — May 2020 [monthly]

    Active Not Recruiting NA

  11. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting NA

  12. Jun 2019 — Dec 2019 [monthly]

    Active Not Recruiting NA

  13. Apr 2019 — Jun 2019 [monthly]

    Active Not Recruiting NA

  14. Nov 2018 — Apr 2019 [monthly]

    Active Not Recruiting NA

  15. Sep 2018 — Nov 2018 [monthly]

    Active Not Recruiting NA

  16. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting NA

  17. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting NA

  18. Aug 2017 — May 2018 [monthly]

    Active Not Recruiting NA

    Phase: PHASE3 → NA

  19. Feb 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE3

  20. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Feb 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Medtronic Cardiovascular
Data source: Medtronic Cardiovascular

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States , Atlanta, United States , Baltimore, United States , Boston, United States , Burlington, United States , Cleveland, United States , Columbus, United States , Dallas, United States , Danville, United States , Des Moines, United States and 28 more locations