deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT01550510

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Phase I/II Study of Intravenous Ascorbic Acid in Combination With Irinotecan Versus Irinotecan Alone for Advanced Colorectal Cancer

Sponsor: Thomas Jefferson University

Conditions Stage IV Colorectal Cancer
Interventions Ascorbic Acid Irinotecan
Updated 13 times since 2017 Last updated: May 2, 2025 Started: Dec 31, 2011 Primary completion: Feb 28, 2015 Completion: Feb 28, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Closed: low enrollment, many treatment options available for Colorectal Cancer

Other terminated trials from Thomas Jefferson University

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Other Stage IV Colorectal Cancer trials with similar outcome

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Listed as NCT01550510, this PHASE1/PHASE2 trial focuses on Stage IV Colorectal Cancer and remains terminated or withdrawn. Sponsored by Thomas Jefferson University, it has been updated 13 times since 2011, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Jul 2019 · 10 months · monthly snapshot~Jul 2019 – ~Nov 2019 · 4 months · monthly snapshot~Nov 2019 – ~Aug 2020 · 9 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – present · 13 months · monthly snapshot

Change History

13 versions recorded

  1. Jun 2025 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Sep 2024 — Jun 2025 [monthly]

    Terminated PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  4. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

  5. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE1_PHASE2

▶ Show 8 earlier versions

  1. Jan 2021 — Dec 2022 [monthly]

    Terminated PHASE1_PHASE2

  2. Aug 2020 — Jan 2021 [monthly]

    Terminated PHASE1_PHASE2

  3. Nov 2019 — Aug 2020 [monthly]

    Terminated PHASE1_PHASE2

  4. Jul 2019 — Nov 2019 [monthly]

    Terminated PHASE1_PHASE2

  5. Sep 2018 — Jul 2019 [monthly]

    Terminated PHASE1_PHASE2

  6. Jun 2018 — Sep 2018 [monthly]

    Terminated PHASE1_PHASE2

  7. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE1_PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE1_PHASE2

    First recorded

Dec 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Thomas Jefferson University
Data source: Thomas Jefferson University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations