Completed PHASE2 INTERVENTIONAL 2-arm NCT01565850

D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive Adults

A Phase 2, Randomized, Double-Blinded Study of the Safety and Efficacy of Darunavir/Cobicistat/Emtricitabine/GS-7340 Single Tablet Regimen Versus Cobicistat-boosted Darunavir Plus Emtricitabine/Tenofovir Disoproxil Fumarate Fixed Dose Combination in HIV-1 Infected, Antiretroviral Treatment Naive Adults

Sponsor: Gilead Sciences

Conditions Acquired Immunodeficiency Syndrome HIV Infections

Interventions COBI COBI Placebo D/C/F/TAF D/C/F/TAF Placebo DRV DRV Placebo FTC/TDF FTC/TDF Placebo

Updated 8 times since 2017 Last updated: Mar 11, 2016 Started: Apr 30, 2012 Primary completion: Jan 31, 2013 Completion: Feb 28, 2014

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Acquired Immunodeficiency Syndrome and HIV Infections and is currently completed. Gilead Sciences leads this study, which shows 8 recorded versions since 2012 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Dec 2021 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Dec 2021 [monthly]

Completed PHASE2

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Apr 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Gilead Sciences

Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Annandale, United States , Berkley, United States , Beverly Hills, United States , Birmingham, United States , Boston, United States , Charlotte, United States , Chicago, United States , Columbia, United States , Dallas, United States , Decatur, United States and 25 more locations