deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT01569438

The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)

A Four-Week, Double-Blind, Placebo-Controlled, Randomized, Multicenter Study Evaluating the Safety and Efficacy of AF-219 in Female Subjects With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

Sponsor: Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Updated 12 times since 2017 Last updated: Aug 6, 2020 Started: Apr 13, 2012 Primary completion: May 1, 2014 Completion: May 14, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This trial was terminated. No reason was provided.

This PHASE2 trial investigates Bladder Pain Syndrome and is currently terminated or withdrawn. Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) leads this study, which shows 12 recorded versions since 2012 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshotCompleted~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshotCompleted~Jun 2018 – ~Jul 2019 · 13 months · monthly snapshotCompleted~Jul 2019 – ~Jul 2020 · 12 months · monthly snapshotCompleted~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshotCompleted~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotTerminated~Jan 2021 – ~Jan 2024 · 36 months · monthly snapshotTerminated~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Jan 2024 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jan 2021 — Jan 2024 [monthly]

    Terminated PHASE2

Show 7 earlier versions
  1. Sep 2020 — Jan 2021 [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

  2. Jul 2020 — Sep 2020 [monthly]

    Completed PHASE2

  3. Jul 2019 — Jul 2020 [monthly]

    Completed PHASE2

  4. Jun 2018 — Jul 2019 [monthly]

    Completed PHASE2

  5. Jul 2017 — Jun 2018 [monthly]

    Completed PHASE2

  6. Feb 2017 — Jul 2017 [monthly]

    Completed PHASE2

  7. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Apr 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Data source: Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

For direct contact, visit the study record on ClinicalTrials.gov .