deltatrials
Active Not Recruiting NA INTERVENTIONAL 1-arm NCT01570998

Intraoperative Radiation Therapy in Treating Patients With Breast Cancer Undergoing Breast-Conserving Surgery

Targeted Intraoperative Radiotherapy United States (TARGIT-US) Phase IV Registry Trial: A Registry Trial of Targeted Intraoperative Radiation Therapy Following Breast-conserving Surgery

Sponsor: Carl Zeiss Meditec AG

Conditions Stage IA Breast Cancer Stage IIA Breast Cancer
Interventions Intraoperative Radiation Therapy Laboratory Biomarker Analysis
Updated 17 times since 2017 Last updated: Feb 4, 2025 Started: May 18, 2012 Primary completion: Dec 31, 2028 Completion: Dec 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Stage IA Breast Cancer and Stage IIA Breast Cancer and is currently ongoing. Carl Zeiss Meditec AG leads this study, which shows 17 recorded versions since 2012 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Nov 2017 · 5 months · monthly snapshot~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Dec 2019 · 7 months · monthly snapshot~Dec 2019 – ~Aug 2020 · 8 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Jul 2023 · 10 months · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

17 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting NA

  2. Mar 2025 — Sep 2025 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  3. Dec 2024 — Mar 2025 [monthly]

    Recruiting NA

  4. Sep 2024 — Dec 2024 [monthly]

    Recruiting NA

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

▶ Show 12 earlier versions

  1. Jul 2023 — Jul 2024 [monthly]

    Recruiting NA

  2. Sep 2022 — Jul 2023 [monthly]

    Recruiting NA

  3. Sep 2021 — Sep 2022 [monthly]

    Recruiting NA

  4. Jan 2021 — Sep 2021 [monthly]

    Recruiting NA

  5. Aug 2020 — Jan 2021 [monthly]

    Recruiting NA

  6. Dec 2019 — Aug 2020 [monthly]

    Recruiting NA

  7. May 2019 — Dec 2019 [monthly]

    Recruiting NA

  8. Jun 2018 — May 2019 [monthly]

    Recruiting NA

  9. Nov 2017 — Jun 2018 [monthly]

    Recruiting NA

    Phase: PHASE4 → NA

  10. Jun 2017 — Nov 2017 [monthly]

    Recruiting PHASE4

  11. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE4

  12. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE4

    First recorded

May 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Carl Zeiss Meditec AG
  • University of California, San Francisco
Data source: University of California, San Francisco

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Baltimore, United States , Berkeley, United States , Burlington, United States , Chicago, United States , Dobbs Ferry, United States , Easton, United States , Fairfax, United States , Fort Lauderdale, United States , Green Bay, United States , Greenwich, United States and 13 more locations