Completed PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT01576328

Safety Study of Mesenchymal Precursor Cells in Type 2 Diabetes

A Randomized, Placebo-Controlled Dose-Escalation Study to Assess the Safety and Tolerability of a Single Intravenous Infusion of Allogeneic Mesenchymal Precursor Cells (MPCs) in Patients With Type 2 Diabetes Sub-optimally Controlled on Metformin

Sponsor: Mesoblast, Ltd.

Conditions Type 2 Diabetes

Interventions Mesenchymal Precursor Cells (MPCs)

Updated 8 times since 2017 Last updated: Jun 1, 2020 Started: Apr 30, 2012 Primary completion: Oct 31, 2013 Completion: Oct 31, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01576328, this PHASE1/PHASE2 trial focuses on Type 2 Diabetes and remains completed. Sponsored by Mesoblast, Ltd., it has been updated 8 times since 2012, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1_PHASE2
Jul 2020 — Jan 2021 [monthly]

Completed PHASE1_PHASE2
Jun 2018 — Jul 2020 [monthly]

Completed PHASE1_PHASE2

▶ Show 3 earlier versions

Mar 2018 — Jun 2018 [monthly]

Completed PHASE1_PHASE2
Feb 2017 — Mar 2018 [monthly]

Completed PHASE1_PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE1_PHASE2

First recorded

Apr 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Mesoblast, Ltd.

Data source: Mesoblast, Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Baton Rouge, United States , Butte, United States , Cincinnati, United States , Dallas, United States , Dayton, United States , Garden Grove, United States , Henderson, United States , Houston, United States , Las Vegas, United States , Miami, United States and 8 more locations