deltatrials
Completed PHASE1 NCT01582295

XL184 For Relapsed/Refractory Multiple Myeloma (MM) With Bone Disease

Dose Finding Pilot Study of Cabozantinib (XL184) Administered Orally as Monotherapy for the Treatment of Patients With Relapsed or Relapsed/Refractory Multiple Myeloma With Bone Disease

Sponsor: Massachusetts General Hospital

Interventions Cabozantinib
Updated 7 times since 2017 Last updated: May 23, 2017 Started: Jun 30, 2012 Primary completion: Aug 31, 2014 Completion: Nov 30, 2014

Listed as NCT01582295, this PHASE1 trial focuses on Multiple Myeloma and remains completed. Sponsored by Massachusetts General Hospital, it has been updated 7 times since 2012, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshotActive Not Recruiting~Mar 2017 – ~Jun 2018 · 15 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 19 months · monthly snapshotCompleted

Change History

7 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1

  5. Mar 2017 — Jun 2018 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 2 earlier versions
  1. Feb 2017 — Mar 2017 [monthly]

    Active Not Recruiting PHASE1

  2. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Jun 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Massachusetts General Hospital
Data source: Massachusetts General Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations