deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT01583218

Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study) (APEX)

(Apex) Multicenter, Randomized, Active-Controlled Efficacy And Safety Study Comparing Extended Duration Betrixaban With Standard Of Care Enoxaparin For The Prevention Of Venous Thromboembolism In Acute Medically Ill Patients

Sponsor: Portola Pharmaceuticals

Updated 11 times since 2017 Last updated: Aug 3, 2023 Started: Mar 31, 2012 Primary completion: Dec 31, 2015 Completion: Jan 31, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Venous Thromboembolism (VTE), this trial is completed. The trial is conducted by Portola Pharmaceuticals and has accumulated 11 data snapshots since 2012. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshotCompleted~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotCompleted~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshotCompleted~Oct 2018 – ~Jan 2021 · 27 months · monthly snapshotCompleted~Jan 2021 – ~Sep 2023 · 32 months · monthly snapshotCompleted~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshotCompleted~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 11 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Dec 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Sep 2023 — Dec 2023 [monthly]

    Completed PHASE3

Show 6 earlier versions
  1. Jan 2021 — Sep 2023 [monthly]

    Completed PHASE3

  2. Oct 2018 — Jan 2021 [monthly]

    Completed PHASE3

  3. Jun 2018 — Oct 2018 [monthly]

    Completed PHASE3

  4. Oct 2017 — Jun 2018 [monthly]

    Completed PHASE3

  5. Feb 2017 — Oct 2017 [monthly]

    Completed PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Mar 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Portola Pharmaceuticals
Data source: Alexion Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .