deltatrials
Active Not Recruiting PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT01629498

Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer

Phase I/II Trial of Image-Guided, Intensity-Modulated Photon (IMRT) or Scanning Beam Proton Therapy (IMPT) Both With Simultaneous Integrated Boost (SIB) Dose Escalation to the Gross Tumor Volume (GTV) With Concurrent Chemotherapy for Stage II/III Non-Small Cell Lung Cancer (NSCLC)

Sponsor: M.D. Anderson Cancer Center

Conditions Recurrent Lung Non-Small Cell Carcinoma Stage II Non-Small Cell Lung Cancer AJCC v7 Stage IIA Non-Small Cell Lung Carcinoma AJCC v7 Stage IIB Non-Small Cell Lung Carcinoma AJCC v7 Stage IIIA Non-Small Cell Lung Cancer AJCC v7 Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions Image Guided Radiation Therapy Intensity-Modulated Radiation Therapy Laboratory Biomarker Analysis Photon Beam Radiation Therapy Proton Beam Radiation Therapy Questionnaire Administration
Updated 19 times since 2017 Last updated: Mar 5, 2026 Started: Sep 17, 2012 Primary completion: Sep 30, 2027 Completion: Sep 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Recurrent Lung Non-Small Cell Carcinoma and Stage II Non-Small Cell Lung Cancer AJCC v7 and is currently ongoing. M.D. Anderson Cancer Center leads this study, which shows 19 recorded versions since 2012 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshot~Sep 2017 – ~Dec 2017 · 3 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshot~Jan 2019 – ~Oct 2019 · 9 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Mar 2023 · 18 months · monthly snapshot~Mar 2023 – ~Sep 2023 · 6 months · monthly snapshot~Sep 2023 – ~Mar 2024 · 6 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Mar 2026 · 5 months · monthly snapshot~Mar 2026 – present · 6 months · monthly snapshot

Change History

19 versions recorded

  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE1/PHASE2

  2. Oct 2025 — Mar 2026 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  3. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Status: Recruiting → Active Not Recruiting

  4. Mar 2025 — Sep 2025 [monthly]

    Recruiting PHASE1/PHASE2

  5. Sep 2024 — Mar 2025 [monthly]

    Recruiting PHASE1/PHASE2

▶ Show 14 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  2. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  3. Sep 2023 — Mar 2024 [monthly]

    Recruiting PHASE1_PHASE2

  4. Mar 2023 — Sep 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Sep 2021 — Mar 2023 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE1_PHASE2

  7. Jan 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Oct 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

  9. Jan 2019 — Oct 2019 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Active Not Recruiting → Recruiting

  10. Jun 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  11. Dec 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  12. Sep 2017 — Dec 2017 [monthly]

    Recruiting PHASE1_PHASE2

  13. Feb 2017 — Sep 2017 [monthly]

    Recruiting PHASE1_PHASE2

  14. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Sep 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • M.D. Anderson Cancer Center
  • National Cancer Institute (NCI)
Data source: M.D. Anderson Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations