An Open-label, Randomized Phase II Study to Evaluate the Efficacy of AUY922 vs Pemetrexed or Docetaxel in NSCLC Patients With EGFR Mutations
A Multicenter, Open-label, Randomized Phase II Study to Evaluate the Efficacy of AUY922 vs Pemetrexed or Docetaxel in NSCLC Patients With EGFR Mutations Who Have Progressed on Prior EGFR TKI Treatment
Sponsor: Novartis Pharmaceuticals
Terminated
An interim analysis was conducted in May-2014. Upon review of the data, the committee recommended study termination due to futility.
A PHASE2 clinical study on Advanced Non Small Cell Lung Cancer (NSCLC), this trial is terminated or withdrawn. The trial is conducted by Novartis Pharmaceuticals and has accumulated 13 data snapshots since 2012. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
13 versions recorded-
Sep 2025 — Present [monthly]
Terminated PHASE2
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Sep 2024 — Sep 2025 [monthly]
Terminated PHASE2
-
Jul 2024 — Sep 2024 [monthly]
Terminated PHASE2
-
Dec 2021 — Jul 2024 [monthly]
Terminated PHASE2
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Jan 2021 — Dec 2021 [monthly]
Terminated PHASE2
▶ Show 8 earlier versions
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Nov 2020 — Jan 2021 [monthly]
Terminated PHASE2
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Aug 2019 — Nov 2020 [monthly]
Terminated PHASE2
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Jun 2018 — Aug 2019 [monthly]
Terminated PHASE2
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May 2018 — Jun 2018 [monthly]
Terminated PHASE2
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Aug 2017 — May 2018 [monthly]
Terminated PHASE2
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May 2017 — Aug 2017 [monthly]
Terminated PHASE2
Status: Completed → Terminated
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Feb 2017 — May 2017 [monthly]
Completed PHASE2
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Jan 2017 — Feb 2017 [monthly]
Completed PHASE2
First recorded
Nov 2012
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Novartis Pharmaceuticals
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Amsterdam, Netherlands , Barcelona, Spain , Bergen, Norway , Créteil, France , Gdansk, Poland , Groningen, Netherlands , Hong Kong, Hong Kong , Koto Ku, Japan , Kuei-Shan Chiang, Taiwan , Leicester, United Kingdom and 14 more locations