deltatrials
Active Not Recruiting NA INTERVENTIONAL 4-arm NCT01652092

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Sponsor: Masonic Cancer Center, University of Minnesota

Conditions Bare Lymphocyte Syndrome CD40 Ligand Deficiency Chediak-Higashi Syndrome Chronic Granulomatous Disease Common Variable Immunodeficiency Griscelli Syndrome Hemophagocytic Lymphohistiocytosis Hyper IgM Syndrome Langerhan's Cell Histiocytosis Omenn's Syndrome Reticular Dysgenesis SCID Wiskott-Aldrich Syndrome X-linked Lymphoproliferative Disease
Interventions Alemtuzumab 0.2 mg Alemtuzumab 0.3 mg Busulfan Cyclophosphamide Fludarabine phosphate 30 mg Fludarabine phosphate 40 mg MESNA Melphalan Stem Cell Transplantation
Updated 14 times since 2017 Last updated: Jan 14, 2026 Started: Sep 4, 2012 Primary completion: Dec 30, 2025 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Bare Lymphocyte Syndrome and CD40 Ligand Deficiency, this trial is ongoing. The trial is conducted by Masonic Cancer Center, University of Minnesota and has accumulated 14 data snapshots since 2012. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Feb 2019 · 4 months · monthly snapshot~Feb 2019 – ~Feb 2020 · 12 months · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~May 2022 · 15 months · monthly snapshot~May 2022 – ~Feb 2023 · 9 months · monthly snapshot~Feb 2023 – ~Feb 2024 · 12 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Feb 2026 · 11 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshot

Change History

14 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  2. Mar 2025 — Feb 2026 [monthly]

    Recruiting NA

  3. Sep 2024 — Mar 2025 [monthly]

    Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. Feb 2024 — Jul 2024 [monthly]

    Recruiting NA

▶ Show 9 earlier versions

  1. Feb 2023 — Feb 2024 [monthly]

    Recruiting NA

  2. May 2022 — Feb 2023 [monthly]

    Recruiting NA

  3. Feb 2021 — May 2022 [monthly]

    Recruiting NA

  4. Jan 2021 — Feb 2021 [monthly]

    Recruiting NA

  5. Feb 2020 — Jan 2021 [monthly]

    Recruiting NA

  6. Feb 2019 — Feb 2020 [monthly]

    Recruiting NA

  7. Oct 2018 — Feb 2019 [monthly]

    Recruiting NA

  8. Jun 2018 — Oct 2018 [monthly]

    Recruiting NA

  9. Jan 2017 — Jun 2018 [monthly]

    Recruiting NA

    First recorded

Sep 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Masonic Cancer Center, University of Minnesota
Data source: Masonic Cancer Center, University of Minnesota

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations