deltatrials
Completed PHASE1 INTERVENTIONAL 17-arm NCT01659255

Study to Evaluate the Safety and Tolerability of Tirabrutinib (ONO/GS-4059) Given as Monotherapy in Participants With Relapsed/Refractory NHL and CLL

An Open-label, Multi-Center, Non-Randomised Phase I Dose-Escalation Study to Investigate the Safety and Tolerability of ONO-4059 (ONO/GS-4059) Given as Monotherapy in Patients With Relapsed/Refractory Non-Hodgkin's Lymphoma (NHL) and Relapsed/Refractory Chronic Lymphocytic Leukaemia (CLL)

Sponsor: Gilead Sciences

Interventions Tirabrutinib
Updated 8 times since 2017 Last updated: Feb 22, 2021 Started: Aug 17, 2012 Primary completion: Feb 23, 2015 Completion: Jan 11, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Chronic Lymphocytic Leukaemia and Non Hodgkins Lymphoma and is currently completed. Gilead Sciences leads this study, which shows 8 recorded versions since 2012 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotCompleted~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshotCompleted~Apr 2021 – ~Jul 2024 · 39 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Apr 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Feb 2021 — Apr 2021 [monthly]

    Completed PHASE1

  5. Jan 2021 — Feb 2021 [monthly]

    Completed PHASE1

Show 3 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1

  2. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE1

  3. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1

    First recorded

Aug 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gilead Sciences
  • Ono Pharmaceutical Co. Ltd
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .