deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT01661101

Management of Myocardial Injury After Noncardiac Surgery Trial (MANAGE)

A Large, International, Randomized, Placebo-controlled Trial to Assess the Impact of Dabigatran (a Direct Thrombin Inhibitor) and Omeprazole (a Proton-pump Inhibitor) in Patients Suffering Myocardial Injury After Noncardiac Surgery

Sponsor: Population Health Research Institute

Updated 9 times since 2017 Last updated: Mar 22, 2018 Started: Jan 31, 2013 Primary completion: Mar 1, 2018 Completion: Mar 1, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Myocardial Injury After Noncardiac Surgery (MINS), this trial is completed. The trial is conducted by Population Health Research Institute and has accumulated 9 data snapshots since 2013. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshotRecruiting~Sep 2017 – ~Apr 2018 · 7 months · monthly snapshotActive Not Recruiting~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

Show 4 earlier versions
  1. Apr 2018 — Jun 2018 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  2. Sep 2017 — Apr 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  3. Feb 2017 — Sep 2017 [monthly]

    Recruiting PHASE3

  4. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Jan 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Population Health Research Institute
Data source: Population Health Research Institute

For direct contact, visit the study record on ClinicalTrials.gov .