Terminated PHASE2 INTERVENTIONAL 2-arm NCT01664637

Diabetic Gastroparesis Efficacy/Safety Study of TZP-102 (DIGEST)

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Evaluation of the Efficacy and Safety of TZP-102 Given Orally Three Times a Day for the Treatment of Symptoms Associated With Diabetic Gastroparesis

Sponsor: Tranzyme, Inc.

Conditions Diabetic Gastroparesis

Interventions 10 mg TZP-102 Placebo

Updated 8 times since 2017 Last updated: Dec 18, 2012 Started: Aug 31, 2012 Primary completion: Jan 31, 2013 Completion: Feb 28, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Insufficient efficacy in planned interim futility analysis

This PHASE2 trial investigates Diabetic Gastroparesis and is currently terminated or withdrawn. Tranzyme, Inc. leads this study, which shows 8 recorded versions since 2012 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Jan 2026 — Present [monthly]

Terminated PHASE2
Sep 2025 — Present [monthly]

Terminated PHASE2
Sep 2024 — Sep 2025 [monthly]

Terminated PHASE2
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE2
Jan 2021 — Jul 2024 [monthly]

Terminated PHASE2

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Terminated PHASE2
Feb 2017 — Jun 2018 [monthly]

Terminated PHASE2
Jan 2017 — Feb 2017 [monthly]

Terminated PHASE2

First recorded

Aug 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Tranzyme, Inc.

Data source: Tranzyme, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Anderson, United States , Bialystok, Poland , Boston, United States , Bydgoszcz, Poland , El Paso, United States , Hialeah, United States , Huntsville, United States , Indianapolis, United States , Inverness, United States , Jacksonville, United States and 22 more locations