deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT01691261

A Study of Implantation of Retinal Pigment Epithelium in Subjects with Acute Wet Age Related Macular Degeneration

Phase 1, Open-label, Safety and Feasibility Study of Implantation of Pf-05206388 (human Embryonic Stem Cell Derived Retinal Pigment Epithelium (rpe) Living Tissue Equivalent) in Subjects with Acute Wet Age Related Macular Degeneration and Recent Rapid Vision Decline

Sponsor: Moorfields Eye Hospital NHS Foundation Trust

Conditions Age Related Macular Degeneration
Interventions PF-05206388
Updated 14 times since 2017 Last updated: Nov 19, 2024 Started: Oct 14, 2021 Primary completion: Oct 10, 2023 Completion: Jun 24, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01691261, this PHASE1 trial focuses on Age Related Macular Degeneration and remains completed. Sponsored by Moorfields Eye Hospital NHS Foundation Trust, it has been updated 14 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jan 2018 · 11 months · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Jan 2019 · 5 months · monthly snapshot~Jan 2019 – ~Jul 2019 · 6 months · monthly snapshot~Jul 2019 – ~Dec 2019 · 5 months · monthly snapshot~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Sep 2022 · 11 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – present · 19 months · monthly snapshot

Change History

14 versions recorded

  1. Dec 2024 — Present [monthly]

    Completed PHASE1

    Status: Unknown → Completed

  2. Sep 2024 — Dec 2024 [monthly]

    Unknown PHASE1

    Status: Recruiting → Unknown

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  4. Sep 2022 — Jul 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  5. Oct 2021 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE1

    Status: Active Not Recruiting → Not Yet Recruiting

▶ Show 9 earlier versions

  1. Jan 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

  2. Dec 2019 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1

  4. Jan 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE1

  5. Aug 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: Suspended → Active Not Recruiting

  6. Jun 2018 — Aug 2018 [monthly]

    Suspended PHASE1

  7. Jan 2018 — Jun 2018 [monthly]

    Suspended PHASE1

  8. Feb 2017 — Jan 2018 [monthly]

    Suspended PHASE1

    Status: Active Not Recruiting → Suspended

  9. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Moorfields Eye Hospital NHS Foundation Trust
  • University College, London
Data source: Moorfields Eye Hospital NHS Foundation Trust

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations