Completed PHASE2 INTERVENTIONAL 2-arm NCT01696279

A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysis

A 3-part Open-label Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Compare the Efficacy, Safety and Tolerability of 8 Weeks of Treatment With Lanthanum Carbonate and Calcium Carbonate Using a Crossover Design and Investigate the Efficacy and Safety of 8 Months of Treatment With Lanthanum Carbonate in Hyperphosphataemic Children and Adolescents Aged 10 Years to <18 Years With Chronic Kidney Disease on Dialysis

Sponsor: Shire

Conditions Chronic Kidney Disease Hyperphosphatemia

Interventions Calcium Carbonate Lanthanum Carbonate

Updated 12 times since 2017 Last updated: May 27, 2021 Started: Feb 15, 2013 Primary completion: Nov 16, 2018 Completion: Nov 16, 2018

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Chronic Kidney Disease and Hyperphosphatemia, this trial is completed. The trial is conducted by Shire and has accumulated 12 data snapshots since 2013. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

12 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Dec 2021 — Jul 2024 [monthly]

Completed PHASE2
Sep 2021 — Dec 2021 [monthly]

Completed PHASE2

▶ Show 7 earlier versions

Jan 2021 — Sep 2021 [monthly]

Completed PHASE2
Feb 2020 — Jan 2021 [monthly]

Completed PHASE2
May 2019 — Feb 2020 [monthly]

Completed PHASE2

Status: Active Not Recruiting → Completed
Dec 2018 — May 2019 [monthly]

Active Not Recruiting PHASE2

Status: Recruiting → Active Not Recruiting
Jun 2018 — Dec 2018 [monthly]

Recruiting PHASE2
Feb 2017 — Jun 2018 [monthly]

Recruiting PHASE2
Jan 2017 — Feb 2017 [monthly]

Recruiting PHASE2

First recorded

Feb 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Shire

Data source: Takeda

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adana, Turkey (Türkiye) , Bialystok, Poland , Budapest, Hungary , Debrecen, Hungary , Erlangen, Germany , Hanover, Germany , Iași, Romania , Izmir, Turkey (Türkiye) , Krakow, Poland , Lodz, Poland and 11 more locations