deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT01708876

P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine (ACT KNOW)

Artesunate-mefloquine vs Chloroquine in Patients With Acute Uncomplicated P. Knowlesi and P. Vivax Malaria: a Randomized Open Label Trial in Sabah, Malaysia

Sponsor: Menzies School of Health Research

Conditions Uncomplicated Plasmodium Knowlesi Malaria
Interventions Artesunate-mefloquine Chloroquine Primaquine
Updated 5 times since 2017 Last updated: Apr 7, 2015 Started: Oct 31, 2012 Primary completion: Dec 31, 2014 Completion: Dec 31, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Uncomplicated Plasmodium Knowlesi Malaria, this trial is completed. The trial is conducted by Menzies School of Health Research and has accumulated 5 data snapshots since 2012. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 23 months · monthly snapshotCompleted

Change History

5 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  4. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

  5. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE3

    First recorded

Oct 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Menzies School of Health Research
  • Ministry of Health, Malaysia
Data source: Menzies School of Health Research

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations