Completed PHASE4 INTERVENTIONAL 2-arm NCT01719978

Hemodynamic and Electrocardiographic Effects of Hyaluronidase Associated With Local Anaesthetics

Hemodynamic and Electrocardiographic Effects of Hyaluronidase Associated With Local Anaesthetics: a Double-blind Split-mouth Controlled Trial.

Sponsor: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Conditions Cardiac Arrhythmias

Interventions 3.6mL 2% Mepivacaine with 1:100,000 epinephrine Hyaluronidase Lower Third Molar Extraction Placebo

Updated 6 times since 2017 Last updated: Oct 31, 2012 Started: Oct 31, 2007 Primary completion: Oct 31, 2007 Completion: Dec 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Cardiac Arrhythmias and is currently completed. Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. leads this study, which shows 6 recorded versions since 2007 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE4
Sep 2024 — Sep 2025 [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jan 2021 — Jul 2024 [monthly]

Completed PHASE4
Jun 2018 — Jan 2021 [monthly]

Completed PHASE4

▶ Show 1 earlier version

Jan 2017 — Jun 2018 [monthly]

Completed PHASE4

First recorded

Oct 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Mauricio Jose Tornelli

Data source: University of Sao Paulo

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• São Paulo, Brazil