deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT01720316

Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders

Pilot Study of Glycine Augmentation in Carriers of a Mutation in the Gene Encoding Glycine Decarboxylase

Sponsor: Mclean Hospital

Interventions Glycine placebo
Updated 10 times since 2017 Last updated: Sep 18, 2017 Started: Dec 10, 2012 Primary completion: May 31, 2017 Completion: May 31, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01720316, this PHASE2 trial focuses on Bipolar Disorder and Schizo-affective Disorder and remains completed. Sponsored by Mclean Hospital, it has been updated 10 times since 2012, reflecting substantial change activity. Mental health research at this phase helps define safety and dosing parameters for future study.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotEnrolling By Invitation~Feb 2017 – ~May 2017 · 3 months · monthly snapshotActive Not Recruiting~May 2017 – ~Aug 2017 · 3 months · monthly snapshotActive Not Recruiting~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. Jan 2021 — Dec 2022 [monthly]

    Completed PHASE2

Show 5 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE2

  2. Aug 2017 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. May 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2017 — May 2017 [monthly]

    Active Not Recruiting PHASE2

    Status: Enrolling By InvitationActive Not Recruiting

  5. Jan 2017 — Feb 2017 [monthly]

    Enrolling By Invitation PHASE2

    First recorded

Dec 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mclean Hospital
  • National Institute of Mental Health (NIMH)
Data source: Mclean Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations