deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT01723020

A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myeloma

A Phase 1 First-in-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 232 in Adult Subjects With Advanced Solid Tumors or Multiple Myeloma

Sponsor: Kartos Therapeutics, Inc.

Interventions AMG 232
Updated 10 times since 2017 Last updated: Aug 30, 2021 Started: Dec 27, 2012 Primary completion: Mar 15, 2017 Completion: Sep 25, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Advanced Malignancy and Advanced Solid Tumors and is currently completed. Kartos Therapeutics, Inc. leads this study, which shows 10 recorded versions since 2012 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~May 2017 · 3 months · monthly snapshotActive Not Recruiting~May 2017 – ~Oct 2017 · 5 months · monthly snapshotActive Not Recruiting~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotCompleted~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 9 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Oct 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. Jan 2021 — Oct 2021 [monthly]

    Completed PHASE1

Show 5 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1

  2. Oct 2017 — Jun 2018 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  3. May 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE1

  4. Feb 2017 — May 2017 [monthly]

    Active Not Recruiting PHASE1

  5. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Dec 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kartos Therapeutics, Inc.
Data source: Kartos Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .