Unknown PHASE4 INTERVENTIONAL 2-arm NCT01745081

Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial Craniotomies

Comparison of the Efficacy Between 20% Mannitol and 3% Hypertonic Saline, Given as a Bolus at the Beginning of Elective Supratentorial Craniotomy for Tumor Resection, in Favoring Cerebral Relaxation Evaluated by a Sub-dural Intracranial Pressure Measurement.

Sponsor: Université de Sherbrooke

Conditions Intracranial Pressure Osmotherapy

Interventions 20% mannitol bolus administration Hypertonic saline 3% bolus administration

Updated 5 times since 2017 Last updated: Dec 6, 2012 Started: Sep 30, 2012 Primary completion: Sep 30, 2014 Completion: Sep 30, 2014

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01745081, this PHASE4 trial focuses on Intracranial Pressure and Osmotherapy and remains ongoing. Sponsored by Université de Sherbrooke, it has been updated 5 times since 2012, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

5 versions recorded

Sep 2024 — Present [monthly]

Unknown PHASE4
Jul 2024 — Sep 2024 [monthly]

Unknown PHASE4

Status: Unknown Status → Unknown
Jan 2021 — Jul 2024 [monthly]

Unknown Status PHASE4
Jun 2018 — Jan 2021 [monthly]

Unknown Status PHASE4
Jan 2017 — Jun 2018 [monthly]

Unknown Status PHASE4

First recorded

Sep 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Université de Sherbrooke

Data source: Université de Sherbrooke

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Sherbrooke, Canada