deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT01747174

REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction (REFLO-STEMI)

Randomized Controlled Trial Comparing Intracoronary Administration of Adenosine or Sodium Nitroprusside to Control for Attenuation of Microvascular Obstruction During Primary Percutaneous Coronary Intervention

Sponsor: University Hospitals, Leicester

Conditions ST-elevation Myocardial Infarction (STEMI)
Interventions IC Adenosine IC Sodium nitroprusside (SNP) Standard PCI
Updated 5 times since 2017 Last updated: Jun 15, 2015 Started: Oct 31, 2011 Primary completion: Oct 31, 2014 Completion: Dec 31, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on ST-elevation Myocardial Infarction (STEMI), this trial is completed. The trial is conducted by University Hospitals, Leicester and has accumulated 5 data snapshots since 2011. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

5 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE2

  5. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE2

    First recorded

Oct 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University Hospitals, Leicester
Data source: University Hospitals, Leicester

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations