deltatrials
Active Not Recruiting OBSERVATIONAL NCT01764529

Modifiers of Disease Severity in Cerebral Cavernous Malformations

Modifiers of Disease Severity and Progression in Cerebral Cavernous Malformations

Sponsor: Alliance to Cure Cavernous Malformation

Conditions Cavernous Angioma, Familial Cerebral Cavernous Hemangioma Cerebral Cavernous Malformations
Updated 20 times since 2017 Last updated: May 22, 2025 Started: Apr 27, 2010 Primary completion: Jun 30, 2025 Completion: Jun 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on Cavernous Angioma, Familial and Cerebral Cavernous Hemangioma, this trial is ongoing. The trial is conducted by Alliance to Cure Cavernous Malformation and has accumulated 20 data snapshots since 2010. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshot~Aug 2017 – ~Mar 2018 · 7 months · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Sep 2019 · 10 months · monthly snapshot~Sep 2019 – ~Jan 2020 · 4 months · monthly snapshot~Jan 2020 – ~Sep 2020 · 8 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Mar 2022 · 3 months · monthly snapshot~Mar 2022 – ~Jan 2023 · 10 months · monthly snapshot~Jan 2023 – ~Jan 2024 · 12 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – present · 13 months · monthly snapshot

Change History

20 versions recorded

  1. Jun 2025 — Present [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  2. Sep 2024 — Jun 2025 [monthly]

    Recruiting

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  4. Jan 2024 — Jul 2024 [monthly]

    Recruiting

  5. Jan 2023 — Jan 2024 [monthly]

    Recruiting

▶ Show 15 earlier versions

  1. Mar 2022 — Jan 2023 [monthly]

    Recruiting

  2. Dec 2021 — Mar 2022 [monthly]

    Recruiting

  3. Jan 2021 — Dec 2021 [monthly]

    Recruiting

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  5. Oct 2020 — Nov 2020 [monthly]

    Recruiting

  6. Sep 2020 — Oct 2020 [monthly]

    Recruiting

  7. Jan 2020 — Sep 2020 [monthly]

    Recruiting

  8. Sep 2019 — Jan 2020 [monthly]

    Recruiting

  9. Nov 2018 — Sep 2019 [monthly]

    Recruiting

  10. Jun 2018 — Nov 2018 [monthly]

    Recruiting

  11. May 2018 — Jun 2018 [monthly]

    Recruiting

  12. Apr 2018 — May 2018 [monthly]

    Recruiting

    Phase: NA → None

  13. Mar 2018 — Apr 2018 [monthly]

    Recruiting NA

  14. Aug 2017 — Mar 2018 [monthly]

    Recruiting NA

  15. Jan 2017 — Aug 2017 [monthly]

    Recruiting NA

    First recorded

Apr 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alliance to Cure Cavernous Malformation
  • Barrow Neurological Institute
  • Boston Children's Hospital
  • Children's Hospital Medical Center, Cincinnati
  • National Institute of Neurological Disorders and Stroke (NINDS)
  • University of California, San Francisco
  • University of Chicago
  • University of New Mexico
Data source: University of California, San Francisco

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations