Completed PHASE4 INTERVENTIONAL 2-arm NCT01768676

Study Evaluating the Effects of Avanafil on Semen Parameters

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Clinical Trial of the Effect of Avanafil (STENDRA™) on Spermatogenesis in Healthy Adult Males and Adult Males With Mild Erectile Dysfunction

Sponsor: VIVUS LLC

Conditions Erectile Dysfunction

Interventions Placebo avanafil

Updated 8 times since 2017 Last updated: Nov 5, 2015 Started: Dec 31, 2012 Primary completion: Aug 31, 2014 Completion: Aug 31, 2014

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01768676, this PHASE4 trial focuses on Erectile Dysfunction and remains completed. Sponsored by VIVUS LLC, it has been updated 8 times since 2012, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE4
Sep 2024 — Sep 2025 [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Mar 2022 — Jul 2024 [monthly]

Completed PHASE4
Jan 2021 — Mar 2022 [monthly]

Completed PHASE4

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE4
Feb 2017 — Jun 2018 [monthly]

Completed PHASE4
Jan 2017 — Feb 2017 [monthly]

Completed PHASE4

First recorded

Dec 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

VIVUS LLC

Data source: VIVUS LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albany, United States , Aventura, United States , Bala-Cynwyd, United States , Carmel, United States , Cincinnati, United States , Huntsville, United States , Kansas City, United States , Knoxville, United States , Los Angeles, United States , New Orleans, United States and 5 more locations