Completed PHASE2 INTERVENTIONAL 1-arm NCT01772953

Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT

A Phase II Study of Treosulfan/Fludarabine/Low Dose Total Body Irradiation as a Preparative Regimen for Children With AML/MDS Undergoing Allogeneic Hematopoietic Cell Transplantation

Sponsor: Center for International Blood and Marrow Transplant Research

Conditions Acute Myeloid Leukemia (AML) Myelodysplastic Syndrome (MDS)

Interventions Treosulfan

Updated 7 times since 2017 Last updated: Oct 10, 2016 Started: Sep 30, 2013 Primary completion: Aug 31, 2015 Completion: Aug 31, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS), this trial is completed. The trial is conducted by Center for International Blood and Marrow Transplant Research and has accumulated 7 data snapshots since 2013. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Sep 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Center for International Blood and Marrow Transplant Research
National Marrow Donor Program
Pediatric Blood and Marrow Transplant Consortium
Resource for Clinical Investigation in Blood and Marrow Transplantation (RCI BMT)
St. Baldrick's Foundation
medac GmbH

Data source: Center for International Blood and Marrow Transplant Research

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States , Aurora, United States , Birmingham, United States , Charleston, United States , Cleveland, United States , Columbus, United States , Duarte, United States , Indianapolis, United States , Kansas City, United States , Los Angeles, United States and 12 more locations