Completed PHASE4 INTERVENTIONAL 1-arm NCT01780389

Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)

Sponsor: Duke University

Conditions Knee Pain After Total Knee Arthroplasty Osteoarthritis Pain

Interventions Open-label flexibly dosed milnacipran

Updated 7 times since 2017 Last updated: Jan 20, 2015 Started: Oct 31, 2010 Primary completion: Jul 31, 2011 Completion: Jul 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Knee Pain After Total Knee Arthroplasty and Osteoarthritis Pain and is currently completed. Duke University leads this study, which shows 7 recorded versions since 2010 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Dec 2021 — Jul 2024 [monthly]

Completed PHASE4
Jan 2021 — Dec 2021 [monthly]

Completed PHASE4
Jun 2018 — Jan 2021 [monthly]

Completed PHASE4

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE4
Jan 2017 — Feb 2017 [monthly]

Completed PHASE4

First recorded

Oct 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Duke University

Data source: Duke University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Durham, United States