deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT01782131

A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)

A Phase 3 Randomized Study of the Efficacy and Safety of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis in Adults and Adolescents (Phase 3; Protocol No. MK-5592-069)

Sponsor: Merck Sharp & Dohme LLC

Conditions Fungal Infections Invasive Pulmonary Aspergillosis
Interventions Placebo Posaconazole Voriconazole
Updated 29 times since 2017 Last updated: Jan 16, 2024 Started: Sep 25, 2013 Primary completion: Jul 10, 2019 Completion: Sep 10, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01782131, this PHASE3 trial focuses on Fungal Infections and Invasive Pulmonary Aspergillosis and remains completed. Sponsored by Merck Sharp & Dohme LLC, it has been updated 29 times since 2013, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~May 2017 · 2 months · monthly snapshot~May 2017 – ~Nov 2017 · 6 months · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Mar 2018 · 3 months · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Dec 2018 · 2 months · monthly snapshot~Dec 2018 – ~Mar 2019 · 3 months · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Jul 2020 · 8 months · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshot~Jun 2022 – ~Feb 2024 · 20 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 24 months · monthly snapshot

Change History

29 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Feb 2024 — Jul 2024 [monthly]

    Completed PHASE3

  4. Jun 2022 — Feb 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Jun 2022 [monthly]

    Completed PHASE3

▶ Show 24 earlier versions

  1. Oct 2020 — Jan 2021 [monthly]

    Completed PHASE3

  2. Sep 2020 — Oct 2020 [monthly]

    Completed PHASE3

  3. Jul 2020 — Sep 2020 [monthly]

    Completed PHASE3

  4. Nov 2019 — Jul 2020 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  5. Sep 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE3

  6. Aug 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE3

  7. Jul 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  8. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  9. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  10. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  11. Dec 2018 — Mar 2019 [monthly]

    Recruiting PHASE3

  12. Oct 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  13. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  14. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  15. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  16. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  17. Apr 2018 — May 2018 [monthly]

    Recruiting PHASE3

  18. Mar 2018 — Apr 2018 [monthly]

    Recruiting PHASE3

  19. Dec 2017 — Mar 2018 [monthly]

    Recruiting PHASE3

  20. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE3

  21. May 2017 — Nov 2017 [monthly]

    Recruiting PHASE3

  22. Mar 2017 — May 2017 [monthly]

    Recruiting PHASE3

  23. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE3

  24. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Sep 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.