Completed INTERVENTIONAL NCT01802099

Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines (NUTRIREA2)

Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines: Multicenter, Randomized Controlled Trial (NUTRIREA-2)

Sponsor: Centre Hospitalier Departemental Vendee

Conditions Acute Respiratory Failure Shock

Interventions Enteral nutrition Parenteral nutrition

Updated 9 times since 2017 Last updated: Mar 26, 2026 Started: Mar 1, 2013 Primary completion: Jul 1, 2015 Completion: Sep 1, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01802099, this observational or N/A phase trial focuses on Acute Respiratory Failure and Shock and remains completed. Sponsored by Centre Hospitalier Departemental Vendee, it has been updated 9 times since 2013, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

9 versions recorded

Apr 17, 2026 — Present [daily]

Completed

Status: Terminated → Completed · Phase: NA → None
Feb 2026 — Apr 2026 [monthly]

Terminated NA
Sep 2025 — Feb 2026 [monthly]

Terminated NA
Sep 2024 — Sep 2025 [monthly]

Terminated NA
Jul 2024 — Sep 2024 [monthly]

Terminated NA

▶ Show 4 earlier versions

Jan 2021 — Jul 2024 [monthly]

Terminated NA
Mar 2019 — Jan 2021 [monthly]

Terminated NA
Jun 2018 — Mar 2019 [monthly]

Terminated NA
Jan 2017 — Jun 2018 [monthly]

Terminated NA

First recorded

Mar 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

The purpose of this study is to assess the hypothesis that, as compared to early intravenous feeding, early nutrition via the enteral route is associated with reduced Day 28-mortality in critically ill patients treated with mechanical ventilation and vasoactive drug.

Contact Information

Sponsor contact:

Centre Hospitalier Departemental Vendee
Institut National de la Santé Et de la Recherche Médicale, France
Ministry of Health, France
University Hospital, Tours

Data source: ClinicalTrials.gov

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Amiens, France , Angers, France , Annecy, France , Beauvais, France , Besançon, France , Bordeaux, France , Chartres, France , Clermont-Ferrand, France , Colombes, France , Dieppe, France and 31 more locations