Completed PHASE3 INTERVENTIONAL 2-arm NCT01813435

GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation

Sponsor: AstraZeneca

Conditions Coronary Artery Disease (CAD)

Interventions Acetylsalicylic Acid Clopidogrel Ticagrelor

Updated 11 times since 2017 Last updated: Mar 13, 2022 Started: Jul 1, 2013 Primary completion: Nov 9, 2015 Completion: Apr 26, 2018

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Coronary Artery Disease (CAD), this trial is completed. The trial is conducted by AstraZeneca and has accumulated 11 data snapshots since 2013. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

Change History

11 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Apr 2022 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Apr 2022 [monthly]

Completed PHASE3

▶ Show 6 earlier versions

Sep 2019 — Jan 2021 [monthly]

Completed PHASE3
Aug 2019 — Sep 2019 [monthly]

Completed PHASE3
Jan 2019 — Aug 2019 [monthly]

Completed PHASE3
Oct 2018 — Jan 2019 [monthly]

Completed PHASE3

Status: Active Not Recruiting → Completed
Jun 2018 — Oct 2018 [monthly]

Active Not Recruiting PHASE3
Jan 2017 — Jun 2018 [monthly]

Active Not Recruiting PHASE3

First recorded

Jul 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

AstraZeneca
Biosensors International
ECRI bv
The Medicines Company

Data source: ECRI bv

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aalst, Belgium , Aix-en-Provence, France , Alkmaar, Netherlands , Amsterdam, Netherlands , Arezzo, Italy , Bad Krozingen, Germany , Bad Nauheim, Germany , Balatonfüred, Hungary , Barcelona, Spain , Belfast, United Kingdom and 96 more locations