Completed EARLY_PHASE1 INTERVENTIONAL 1-arm NCT01825902

18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma

A Pilot Study of the Utility of 18F-FLT-PET and Diffusion-Weighted MRI for Surgical Planning, Radiotherapy Target Delineation, and Treatment Response Evaluation in Ewing Sarcoma Patients

Sponsor: Mayo Clinic

Conditions Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) Ewing Sarcoma of Bone Extraosseous Ewing Sarcoma Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

Interventions diffusion-weighted magnetic resonance imaging fludeoxyglucose F 18 fluorine F 18 fluorothymidine laboratory biomarker analysis positron emission tomography

Updated 9 times since 2017 Last updated: Nov 16, 2017 Started: Mar 31, 2013 Primary completion: Jan 31, 2014 Completion: Nov 23, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This EARLY_PHASE1 trial investigates Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) and Ewing Sarcoma of Bone and is currently completed. Mayo Clinic leads this study, which shows 9 recorded versions since 2013 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

9 versions recorded

Sep 2024 — Present [monthly]

Completed EARLY_PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed EARLY_PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed EARLY_PHASE1
Jun 2018 — Jan 2021 [monthly]

Completed EARLY_PHASE1
Dec 2017 — Jun 2018 [monthly]

Completed EARLY_PHASE1

Phase: NA → EARLY_PHASE1

▶ Show 4 earlier versions

Jun 2017 — Dec 2017 [monthly]

Completed NA
Apr 2017 — Jun 2017 [monthly]

Completed NA

Status: Active Not Recruiting → Completed
Feb 2017 — Apr 2017 [monthly]

Active Not Recruiting NA
Jan 2017 — Feb 2017 [monthly]

Active Not Recruiting NA

First recorded

Mar 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Mayo Clinic

Data source: Mayo Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Rochester, United States