deltatrials
Completed NA INTERVENTIONAL 2-arm NCT01832753

Treatment Trial of Subclinical Hypothyroidism in Down Syndrome

Levothyroxine Treatment and Cardiometabolic Outcomes in Adolescents With Down Syndrome

Sponsor: Children's Hospital of Philadelphia

Conditions Down Syndrome Subclinical Hypothyroidism
Interventions Levothyroxine
Updated 15 times since 2017 Last updated: Sep 4, 2019 Started: Jan 31, 2013 Primary completion: Oct 18, 2017 Completion: Oct 18, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01832753, this NA trial focuses on Down Syndrome and Subclinical Hypothyroidism and remains completed. Sponsored by Children's Hospital of Philadelphia, it has been updated 15 times since 2013, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshot~Jul 2017 – ~Dec 2017 · 5 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Jul 2019 · 8 months · monthly snapshot~Jul 2019 – ~Oct 2019 · 3 months · monthly snapshot~Oct 2019 – ~Jan 2021 · 15 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed NA

  2. Sep 2024 — Sep 2025 [monthly]

    Completed NA

  3. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  4. Jan 2023 — Jul 2024 [monthly]

    Completed NA

  5. Dec 2022 — Jan 2023 [monthly]

    Completed NA

▶ Show 10 earlier versions

  1. Dec 2021 — Dec 2022 [monthly]

    Completed NA

  2. Jan 2021 — Dec 2021 [monthly]

    Completed NA

  3. Oct 2019 — Jan 2021 [monthly]

    Completed NA

    Status: Active Not Recruiting → Completed

  4. Jul 2019 — Oct 2019 [monthly]

    Active Not Recruiting NA

  5. Nov 2018 — Jul 2019 [monthly]

    Active Not Recruiting NA

  6. Jun 2018 — Nov 2018 [monthly]

    Active Not Recruiting NA

  7. Dec 2017 — Jun 2018 [monthly]

    Active Not Recruiting NA

  8. Jul 2017 — Dec 2017 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  9. Feb 2017 — Jul 2017 [monthly]

    Recruiting NA

  10. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Jan 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Hospital of Philadelphia
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Data source: Children's Hospital of Philadelphia

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations