deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT01834248

DEC-205/NY-ESO-1 Fusion Protein CDX-1401and Decitabine in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

A Phase I Study of DEC205mAb-NY-ESO-1 Fusion Protein (CDX-1401) Given With Adjuvant PoIylCLC in Conjunction With 5-Aza-2'Deoxycytidine (Decitabine) in Patients With MDS or Low Blast Count AML

Sponsor: Roswell Park Cancer Institute

Updated 10 times since 2017 Last updated: Jul 20, 2022 Started: Jul 30, 2013 Primary completion: Jun 9, 2015 Completion: Mar 21, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Acute Myeloid Leukemia and Alkylating Agent-Related Acute Myeloid Leukemia and is currently completed. Roswell Park Cancer Institute leads this study, which shows 10 recorded versions since 2013 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotActive Not Recruiting~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2020 · 19 months · monthly snapshotCompleted~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshotCompleted~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshotCompleted~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotCompleted~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Sep 2022 [monthly]

    Completed PHASE1

  5. Feb 2020 — Jan 2021 [monthly]

    Completed PHASE1

Show 5 earlier versions
  1. Jan 2020 — Feb 2020 [monthly]

    Completed PHASE1

  2. Jun 2018 — Jan 2020 [monthly]

    Completed PHASE1

  3. Aug 2017 — Jun 2018 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  4. Feb 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE1

  5. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Jul 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Roswell Park Cancer Institute
Data source: Roswell Park Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations