deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 4-arm NCT01835067

Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD (TAPAS)

Intravitreal Tissue Plasminogen Activator And Perfluoropropane for Neovascular Age-related Macular Degeneration With Associated Submacular Haemorrhage: a Multi-centre, Randomized, Double-masked, Sham-controlled, Factorial, Feasibility Study

Sponsor: King's College Hospital NHS Trust

Updated 10 times since 2017 Last updated: Jul 10, 2020 Started: Sep 30, 2014 Primary completion: Nov 30, 2019 Completion: Dec 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2/PHASE3 trial investigates Exudative Macular Degeneration and Retinal Hemorrhage and is currently completed. King's College Hospital NHS Trust leads this study, which shows 10 recorded versions since 2014 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2018 · 13 months · monthly snapshotRecruiting~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotUnknown Status~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotUnknown Status~Aug 2018 – ~Jun 2019 · 10 months · monthly snapshotRecruiting~Jun 2019 – ~Mar 2020 · 9 months · monthly snapshotActive Not Recruiting~Mar 2020 – ~Aug 2020 · 5 months · monthly snapshotActive Not Recruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

  4. Aug 2020 — Jan 2021 [monthly]

    Completed PHASE2_PHASE3

    Status: Active Not RecruitingCompleted

  5. Mar 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

Show 5 earlier versions
  1. Jun 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: RecruitingActive Not Recruiting

  2. Aug 2018 — Jun 2019 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Unknown StatusRecruiting

  3. Jun 2018 — Aug 2018 [monthly]

    Unknown Status PHASE2_PHASE3

  4. Feb 2018 — Jun 2018 [monthly]

    Unknown Status PHASE2_PHASE3

    Status: RecruitingUnknown Status

  5. Jan 2017 — Feb 2018 [monthly]

    Recruiting PHASE2_PHASE3

    First recorded

Sep 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • King's College Hospital NHS Trust
Data source: King's College Hospital NHS Trust

For direct contact, visit the study record on ClinicalTrials.gov .