deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT01853982

Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated Pneumonia

A Multicenter, Open-Label, Randomized Study to Compare the Safety and Efficacy of Intravenous Ceftolozane/Tazobactam With That of Piperacillin/Tazobactam in Ventilator Associated Pneumonia

Sponsor: Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Updated 10 times since 2017 Last updated: Oct 18, 2018 Started: Jun 14, 2013 Primary completion: Nov 20, 2013 Completion: Dec 8, 2013
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Terminated to focus on a larger study within the clinical development program.

This PHASE3 trial investigates Ventilator-Associated Pneumonia (VAP) and is currently terminated or withdrawn. Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) leads this study, which shows 10 recorded versions since 2013 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshotTerminated~Dec 2018 – ~Jan 2021 · 25 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jan 2024 · 25 months · monthly snapshotTerminated~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 12 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Jan 2024 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Dec 2021 — Jan 2024 [monthly]

    Terminated PHASE3

Show 5 earlier versions
  1. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

  2. Dec 2018 — Jan 2021 [monthly]

    Terminated PHASE3

  3. Jun 2018 — Dec 2018 [monthly]

    Terminated PHASE3

  4. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  5. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Jun 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Data source: Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

For direct contact, visit the study record on ClinicalTrials.gov .