deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT01862900

Stereotactic Body Radiation and Monoclonal Antibody to OX40 (MEDI6469) in Breast Cancer Patients With Metastatic Lesions (OX40 Breast)

Phase I/II Study of Stereotactic Body Radiation Therapy to Metastatic Lesions in the Liver or Lung in Combination With Monoclonal Antibody to OX40 (MEDI6469) in Patients With Progressive Metastatic Breast Cancer After Systemic Therapy.

Sponsor: MedImmune LLC

Interventions MEDI6469
Updated 9 times since 2017 Last updated: Mar 19, 2019 Started: Apr 27, 2012 Primary completion: May 17, 2016 Completion: Aug 15, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01862900, this PHASE1 trial focuses on Liver Metastases and Lung Metastases and remains completed. Sponsored by MedImmune LLC, it has been updated 9 times since 2012, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotRecruiting~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotActive Not Recruiting~Sep 2018 – ~Apr 2019 · 7 months · monthly snapshotActive Not Recruiting~Apr 2019 – ~Jan 2021 · 21 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Apr 2019 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted · Phase: PHASE1_PHASE2PHASE1

  5. Sep 2018 — Apr 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

Show 4 earlier versions
  1. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Aug 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  3. Feb 2017 — Aug 2017 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Apr 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MedImmune LLC
  • Providence Cancer Center, Earle A. Chiles Research Institute
  • Providence Health & Services
  • Robert W. Franz Cancer Center
Data source: Providence Health & Services

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations