Completed PHASE2 INTERVENTIONAL 2-arm NCT01867697

Nordic 8 - A Phase II Trial

Potentially Resectable Metastatic Colorectal Cancer With Wild-type KRAS and BRAF: Alternating Chemotherapy Plus Cetuximab - A Randomised Phase II Trial

Sponsor: Merck Serono International SA

Conditions Metastatic Colorectal Cancer

Interventions Calcium Carbonate Cetuximab Folinic Acid Irinotecan Oxaliplatin

Updated 9 times since 2017 Last updated: Oct 29, 2020 Started: May 31, 2012 Primary completion: Mar 31, 2019 Completion: Mar 31, 2019

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01867697, this PHASE2 trial focuses on Metastatic Colorectal Cancer and remains completed. Sponsored by Merck Serono International SA, it has been updated 9 times since 2012, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE2
Nov 2020 — Jan 2021 [monthly]

Completed PHASE2

Status: Unknown Status → Completed

▶ Show 4 earlier versions

Sep 2020 — Nov 2020 [monthly]

Unknown Status PHASE2

Status: Active Not Recruiting → Unknown Status
Sep 2018 — Sep 2020 [monthly]

Active Not Recruiting PHASE2

Status: Unknown Status → Active Not Recruiting
Jun 2018 — Sep 2018 [monthly]

Unknown Status PHASE2
Jan 2017 — Jun 2018 [monthly]

Unknown Status PHASE2

First recorded

May 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Merck Serono International SA
Per Pfeiffer

Data source: Odense University Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aalborg, Denmark , Aarhus, Denmark , Bergen, Norway , Copenhagen, Denmark , Esbjerg, Denmark , Herlev, Denmark , Herning, Denmark , Næstved, Denmark , Odense, Denmark , Roskilde, Denmark and 2 more locations