deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 10-arm NCT01877421

Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population (APCG)

A Double-Blind, Randomized, Controlled, Dose Escalation Clinical Trial of an Antiplaque Chewing Gum - Phase 1 Safety and Tolerability and Phase 2a Safety, Tolerability, and Proof of Concept in a Gingivitis Population

Sponsor: U.S. Army Medical Research and Development Command

Conditions Gingivitis Plaque
Interventions 10 mg KSL-W 100 mg KSL-W 2 mg KSL-W 20 mg KSL-W 30 mg KSL-W 4 mg KSL-W 50 mg KSL-W 6 mg KSL-W 75 mg KSL-W Placebo
Updated 9 times since 2017 Last updated: Feb 11, 2020 Started: Feb 25, 2014 Primary completion: Aug 25, 2015 Completion: Mar 31, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Gingivitis and Plaque and is currently completed. U.S. Army Medical Research and Development Command leads this study, which shows 9 recorded versions since 2014 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshotCompleted~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotCompleted~Jun 2018 – ~Aug 2019 · 14 months · monthly snapshotCompleted~Aug 2019 – ~Mar 2020 · 7 months · monthly snapshotCompleted~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

9 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Mar 2020 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  5. Aug 2019 — Mar 2020 [monthly]

    Completed PHASE1_PHASE2

▶ Show 4 earlier versions

  1. Jun 2018 — Aug 2019 [monthly]

    Completed PHASE1_PHASE2

  2. Oct 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

  3. Feb 2017 — Oct 2017 [monthly]

    Completed PHASE1_PHASE2

  4. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1_PHASE2

    First recorded

Feb 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • U.S. Army Medical Research and Development Command
Data source: U.S. Army Medical Research and Development Command

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations