deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT01877915

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure (COMMANDER HF)

A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban With Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects With Heart Failure and Significant Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Sponsor: Bayer

Updated 19 times since 2017 Last updated: Apr 18, 2019 Started: Sep 10, 2013 Primary completion: Apr 19, 2018 Completion: Apr 19, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01877915, this PHASE3 trial focuses on Coronary Artery Disease and Heart Failure and remains completed. Sponsored by Bayer, it has been updated 19 times since 2013, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~May 2017 · 2 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Sep 2017 · 2 months · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Feb 2018 · 3 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Jun 2019 · 9 months · monthly snapshot~Jun 2019 – ~Jan 2021 · 19 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 10 months · monthly snapshot

Change History

19 versions recorded
  1. Oct 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2025 — Oct 2025 [monthly]

    Completed PHASE3

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

Show 14 earlier versions
  1. Jun 2019 — Jan 2021 [monthly]

    Completed PHASE3

  2. Sep 2018 — Jun 2019 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

  4. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  5. Feb 2018 — Mar 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Nov 2017 — Feb 2018 [monthly]

    Recruiting PHASE3

  7. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE3

  8. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  9. Jul 2017 — Sep 2017 [monthly]

    Recruiting PHASE3

  10. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE3

  11. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

  12. Mar 2017 — May 2017 [monthly]

    Recruiting PHASE3

  13. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE3

  14. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Sep 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bayer
  • Janssen Research & Development, LLC
Data source: Janssen Research & Development, LLC

For direct contact, visit the study record on ClinicalTrials.gov .