deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT01882764

HMPL-004 Maintenance Treatment in Subjects With Mild to Moderate Ulcerative Colitis (NATRUL-4)

A Phase III Double Blind, Multi-Center Placebo Controlled Maintenance Trial of HMPL-004 in Subjects With Mild to Moderate Ulcerative Colitis With Clinical Remission or Response From Induction Therapy. (NATRUL-4)

Sponsor: Hutchison Medipharma Limited

Interventions HMPL-004 Placebo
Updated 11 times since 2017 Last updated: Dec 26, 2019 Started: Jun 30, 2013 Primary completion: Oct 31, 2014 Completion: Oct 31, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Futility interim analysis of the Induction Study HMPL-004-03.

This PHASE3 trial investigates Ulcerative Colitis and is currently terminated or withdrawn. Hutchison Medipharma Limited leads this study, which shows 11 recorded versions since 2013 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Mar 2019 · 9 months · monthly snapshotTerminated~Mar 2019 – ~Feb 2020 · 11 months · monthly snapshotTerminated~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshotTerminated~Jan 2021 – ~Oct 2022 · 21 months · monthly snapshotTerminated~Oct 2022 – ~Dec 2022 · 2 months · monthly snapshotTerminated~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotTerminated~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 24 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  3. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE3

  4. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE3

  5. Oct 2022 — Dec 2022 [monthly]

    Terminated PHASE3

Show 6 earlier versions
  1. Jan 2021 — Oct 2022 [monthly]

    Terminated PHASE3

  2. Feb 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  3. Mar 2019 — Feb 2020 [monthly]

    Terminated PHASE3

  4. Jun 2018 — Mar 2019 [monthly]

    Terminated PHASE3

  5. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Jun 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hutchison Medipharma Limited
  • Nutrition Science Partners Limited
Data source: Hutchmed

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations