deltatrials
Recruiting PHASE2 INTERVENTIONAL 1-arm NCT01889381

Human Craniomaxillofacial Allotransplantation

Sponsor: Johns Hopkins University

Conditions Craniofacial Defects Craniofacial Injuries Facial Deformity Facial Injuries Facial Transplantation Traumatic Wounds and Injuries
Interventions Bone marrow cell-based therapy & 1-drug immunosuppression.
Updated 14 times since 2017 Last updated: Aug 11, 2025 Started: Aug 31, 2012 Primary completion: Aug 31, 2026 Completion: Aug 31, 2031
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01889381, this PHASE2 trial focuses on Craniofacial Defects and Craniofacial Injuries and remains actively recruiting participants. Sponsored by Johns Hopkins University, it has been updated 14 times since 2012, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Oct 2017 · 9 months · monthly snapshot~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~May 2019 · 6 months · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~May 2020 · 9 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Sep 2023 · 12 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded

  1. Sep 2025 — Present [monthly]

    Recruiting PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  4. Sep 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

  5. Sep 2022 — Sep 2023 [monthly]

    Recruiting PHASE2

▶ Show 9 earlier versions

  1. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE2

  2. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  3. May 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  4. Aug 2019 — May 2020 [monthly]

    Recruiting PHASE2

  5. May 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  6. Nov 2018 — May 2019 [monthly]

    Recruiting PHASE2

  7. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  8. Oct 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  9. Jan 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

    First recorded

Aug 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Johns Hopkins University
Data source: Johns Hopkins University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations