deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT01913353

A Non-inferiority Trial to Compare MVA-BN® Smallpox Vaccine to ACAM2000®

A Randomized, Open-label Phase III Non-inferiority Trial to Compare Indicators of Efficacy for MVA-BN® Smallpox Vaccine to ACAM2000® in 18-42 Year Old Healthy Vaccinia-naïve Subjects

Sponsor: Bavarian Nordic

Updated 11 times since 2017 Last updated: Nov 18, 2019 Started: Mar 31, 2015 Primary completion: Mar 31, 2017 Completion: Aug 31, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on 18-42 Year Old Healthy Vaccinia-naïve Subjects, this trial is completed. The trial is conducted by Bavarian Nordic and has accumulated 11 data snapshots since 2015. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotActive Not Recruiting~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Aug 2019 · 14 months · monthly snapshotActive Not Recruiting~Aug 2019 – ~Jan 2020 · 5 months · monthly snapshotUnknown Status~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshotCompleted~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotCompleted~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Oct 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Oct 2021 [monthly]

    Completed PHASE3

Show 6 earlier versions
  1. Jan 2020 — Jan 2021 [monthly]

    Completed PHASE3

    Status: Unknown StatusCompleted

  2. Aug 2019 — Jan 2020 [monthly]

    Unknown Status PHASE3

    Status: Active Not RecruitingUnknown Status

  3. Jun 2018 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

  4. Aug 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  5. Feb 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bavarian Nordic
  • US Army Medical Research Institute of Infectious Diseases
Data source: Bavarian Nordic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations