deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT01925274

A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer

A RANDOMIZED PHASE 2 STUDY OF PF-05212384 PLUS IRINOTECAN VERSUS CETUXIMAB PLUS IRINOTECAN IN PATIENTS WITH KRAS AND NRAS WILD TYPE METASTATIC COLORECTAL CANCER

Sponsor: Pfizer

Updated 14 times since 2017 Last updated: Dec 19, 2018 Started: Nov 15, 2013 Primary completion: Apr 6, 2016 Completion: Apr 6, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Enrollment to the study was terminated on 11Nvo2014 due to slow recruitment. There were no safety or efficacy issues that contributed to this decision.

This PHASE2 trial investigates Metastatic Colorectal Cancer and is currently terminated or withdrawn. Pfizer leads this study, which shows 14 recorded versions since 2013 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~May 2018 · 9 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Nov 2020 · 21 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

Show 9 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  2. Feb 2019 — Nov 2020 [monthly]

    Terminated PHASE2

  3. Jun 2018 — Feb 2019 [monthly]

    Terminated PHASE2

  4. May 2018 — Jun 2018 [monthly]

    Terminated PHASE2

  5. Aug 2017 — May 2018 [monthly]

    Terminated PHASE2

  6. Jul 2017 — Aug 2017 [monthly]

    Terminated PHASE2

  7. Jun 2017 — Jul 2017 [monthly]

    Terminated PHASE2

  8. Feb 2017 — Jun 2017 [monthly]

    Terminated PHASE2

  9. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE2

    First recorded

Nov 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .