deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT01927744

Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical Resection

Randomized, Placebo-Controlled, Phase 2 Study Of Induction Chemotherapy With Cisplatin/Carboplatin, And Docetaxel With Or Without Erlotinib In Patients With Head And Neck Squamous Cell Carcinomas Amenable For Surgical Resection

Sponsor: Astellas Pharma Inc

Conditions Head and Neck Cancer
Interventions Chemotherapy Docetaxel Erlotinib Phone Call Placebo Questionnaires
Updated 23 times since 2017 Last updated: Nov 14, 2025 Started: Dec 16, 2013 Primary completion: Jan 6, 2025 Completion: Jan 6, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Head and Neck Cancer, this trial is completed. The trial is conducted by Astellas Pharma Inc and has accumulated 23 data snapshots since 2013. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Feb 2018 · 6 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Mar 2019 · 9 months · monthly snapshot~Mar 2019 – ~Jun 2019 · 3 months · monthly snapshot~Jun 2019 – ~Jan 2020 · 7 months · monthly snapshot~Jan 2020 – ~Sep 2020 · 8 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshot~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshot~Sep 2022 – ~Jul 2023 · 10 months · monthly snapshot~Jul 2023 – ~Oct 2023 · 3 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~May 2024 · 6 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Feb 2025 · 3 months · monthly snapshot~Feb 2025 – ~Dec 2025 · 10 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

23 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE2

  2. Feb 2025 — Dec 2025 [monthly]

    Completed PHASE2

    Status: Recruiting → Completed

  3. Nov 2024 — Feb 2025 [monthly]

    Recruiting PHASE2

  4. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE2

  5. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

▶ Show 18 earlier versions

  1. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  2. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  3. Nov 2023 — May 2024 [monthly]

    Recruiting PHASE2

  4. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE2

    Status: Active Not Recruiting → Recruiting

  5. Jul 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2

  6. Sep 2022 — Jul 2023 [monthly]

    Active Not Recruiting PHASE2

  7. Mar 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  8. Jan 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2

  9. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  10. Jan 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  11. Jun 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

  12. Mar 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  13. Jun 2018 — Mar 2019 [monthly]

    Active Not Recruiting PHASE2

  14. Feb 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  15. Aug 2017 — Feb 2018 [monthly]

    Recruiting PHASE2

  16. Jun 2017 — Aug 2017 [monthly]

    Recruiting PHASE2

  17. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  18. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Dec 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Astellas Pharma Inc
  • M.D. Anderson Cancer Center
  • The Kadoorie Charitable Foundations
Data source: M.D. Anderson Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations